Breakthrough CRISPR Technology Study Published in Nature

Benson Hill’s world-class scientists discover new mechanism for CRISPR technology that detects RNA ST. LOUIS–(BUSINESS WIRE)– $BHIL #BHIL –A groundbreaking research study by a team that included scientists from Benson Hill , Inc. (NYSE: BHIL, the “Company” or “Benson Hill”), has been published this month in Nature, the world’s leading multidisciplinary journal, highlighting a new mechanism for Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) technology. The research paper, titled “Cas12a2 elicits abortive infection via RNA-triggered destruction of dsDNA,” discusses the discovery of a new enzymatic capability for CRISPR systems, opening the possibility of using CRISPR in new applications beyond gene editing – including cancer therapeutics, programmable shaping of microbial communities, and counterselection to enhance gene editing. As part of its work to unlock the genetic diversity of plants, Benson Hill’s team collaborated with members of its Scientific Advisory Board, including university scientists from the U.S. and Germany, to uncover insights and solve a complex biological problem for how CRISPR enzymes work. In doing so, they discovered the underlying biology and a new mechanism for how CRISPR nucleases, specifically Cas12a2, can function. The study concludes that Cas12a2 holds substantial potential for CRISPR technologies as a biotechnological tool. In a proof-of-principle […]

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