B7-H3 Immune Checkpoint Inhibitor Clinical Trials Market Opportunity Insight Kuick Research Study Highlights Current Clinical Trials Landscape & Commercial market Opportunity Asessment Delhi, Feb. 24, 2023 (GLOBE NEWSWIRE) — Over the years, immune checkpoint inhibition has developed itself as one of the cornerstones in cancer therapy arising from their otherwise detrimental role in cancer. The immunosuppressive environment created because of immune checkpoint proteins harbors an apt environment for the proliferation of cancer cells. Therefore, inhibition of checkpoint proteins has become an essential and emerging strategy for cancer treatment. Post the identification of immune checkpoints, research studies were focused on identifying more immune checkpoints and the B7-H3 was one of those discovered in the early 2000s. The protein has certain properties that make it different from other immune checkpoints, increasing the interest of researchers and drug developers looking for a novel protein to target to treat cancer. Global CD276 Antibody Clinical Trials & Market Sales Forecast 2028 Report Highlights: Global CD276 Antibody Market Opportunity Assessment: > US$ 1 Billion Global CD276 Antibody Expected Drug Approvals Global CD276 Antibody Clinical Trials: > 30 Drugs In Trials Targeting CD276 Through Monotherapy, Combination & Targeted Therapy CD276 Antibodies Orphan & Priority Status Review […]

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Mindful Media VanEck Environmental Services ETF (NYSEARCA: EVX ) has a reasonably balanced allocation of investments from a market capitalization standpoint, providing diversification in company sizes. EVX is uniquely focused on companies with products and services currently in demand due to increasing environmental conservation. Despite that promising concept, near-term headwinds toward the broad stock market could hamper potential future performance for EVX. This ETF is based on a solid concept and has long-term growth potential. However, keeping in mind the risk factors I cite below, I rate EVX a Hold for now. Strategy EVX seeks to replicate the performance of its underlying index, the NYSE Arca Environmental Services Index (AXENV). That index tracks the performance of businesses involved in a diverse set of environmental services, including waste disposal, soil remediation, wastewater management, recycling, and environmental consulting. EVX uses a full replication strategy and indexing investment approach to achieve its objective of tracking the index’s performance. Holding Analysis EVX has 24 holdings, with a concentration at the top. Ecolab Inc. ( ECL ) accounts for about 10% all by itself. And 3 other stocks, Waste Connections Inc. ( WCN ), Republic Services Inc. ( RSG ), and Waste Management Inc. […]

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Papaya Growth Opportunity Corp. I Hsbc Holdings PLC purchased a new stake in Papaya Growth Opportunity Corp. I ( NASDAQ:PPYA – Get Rating ) during the 3rd quarter, according to its most recent Form 13F filing with the Securities & Exchange Commission. The fund purchased 747,074 shares of the company’s stock, valued at approximately $7,493,000. Hsbc Holdings PLC owned 1.98% of Papaya Growth Opportunity Corp. I as of its most recent filing with the Securities & Exchange Commission. A number of other institutional investors and hedge funds have also recently modified their holdings of the business. Sage Mountain Advisors LLC acquired a new position in shares of Papaya Growth Opportunity Corp. I during the second quarter valued at about $46,000. State Street Corp purchased a new position in shares of Papaya Growth Opportunity Corp. I in the second quarter worth about $184,000. Virtu Financial LLC purchased a new position in shares of Papaya Growth Opportunity Corp. I in the second quarter valued at $220,000. Prelude Capital Management LLC bought a new position in Papaya Growth Opportunity Corp. I in the 1st quarter valued at $368,000. Finally, Cubist Systematic Strategies LLC bought a new position in shares of Papaya Growth […]

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Are small caps the place to be right now? They look like better value than the S&P 500 itself, which, in an environment that seems to vacillate wildly between soft-landing optimism and hard-landing, Fed-induced recession pessimism, is certainly worth taking a look at. That small cap opportunity may prompt investors to take a look at a duo of ETFs from American Century Investment’s brand Avantis Investors, the Avantis U.S Small Cap Equity ETF ( AVSC ) and the Avantis U.S. Small Cap Value ETF ( AVUV ). What is driving small caps’ value moment relative to the big S&P 500? Based on trailing operating earnings, small caps are seeing at a 25% discount to large caps, one of the biggest discounts since the mid-1980s – they’re also trading at 16 times earnings on aggregate based on forecast earnings according to the Leuthold Group . Compare that to 19 times for large caps, for example, too. Advisors themselves are already showing their hunger for small caps . On a year-to-date basis, meanwhile, small cap value as an equity factor was the second strongest based on returns, while small cap core and small cap growth rounded out the top five . […]

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Vacancy An opportunity to shape, deliver and secure the future systems and platforms for a world renowned British cybersecurity software business with robust security requirements. Background Based in Cheshire in the United Kingdom, PortSwigger is a global leader in the cybersecurity sector. Our cutting-edge software is used by over 50,000 customers in 150 countries to help them secure their web applications. We go beyond just selling software. Our educational and research output is used by millions of people globally to learn about web security. We first made our name with Burp Suite, the leading software for web penetration testing. We have since broadened our focus with the release of Burp Suite Enterprise Edition, which is aimed at software development teams and large organizations with extensive web assets to defend, and the Web Security Academy. Our software products include our customer-facing website, the Customer Success Platform. We are a fun group of people from a diverse range of backgrounds, who pull together to produce amazing outcomes for our customers. We achieve this by continually investing in and supporting our people, giving them opportunities to flourish in our supportive and collaborative working environment. Humans aren’t resources. PortSwigger is its people; they […]

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Already a member? Sign In U.S. Clean Energy Is Attracting Billions. 5 Key Players. Enphase sees strong demand for its made-in-America gear for solar panels. A boom in clean-energy manufacturing is fast getting under way across the U.S. Factories are suddenly cranking out everything from solar and wind equipment to batteries and low-carbon fuel. Corporate investment dollars, spurred by new tax breaks, are transforming the U.S. from an also-ran in alternative energy to a real player, lifting the fortunes of a number of companies. Since President Joe Biden earmarked $370 billion for clean energy in the Inflation Reduction Act in August, there have been 76 announcements of clean-energy projects, notes Credit Suisse Of those, 40 specified dollar amounts, totaling $77 billion.

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MarketWatch Buttigieg inspects Ohio disaster site as NTSB report points to excessive train-wheel bearing temperature before derailment Norfolk Southern train’s bearing-temperature detector recorded a higher-than-acceptable temperature of 253º Fahrenheit before the crash, says National Transportation Safety Board. Reuters Ford halts F-150 EV production for another week after battery fire The development comes days after The National Highway Traffic Safety Administration (NHTSA) said it is holding talks with Ford over the issue. SK On, a South Korean EV battery maker and supplier to Ford, has again started building battery cells at a plant in Georgia. "It will take SK time to ensure they are back to building high-quality cells and to deliver them to the Lightning production line," Ford said in a statement. Benzinga European Authority Recommends Against Approval For Merck-Ridgeback Biotherapeutics’ COVID-19 Pill Merck & Co Inc (NYSE: MRK) and Ridgeback Biotherapeutics announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) had recommended the refusal of the marketing authorization for Lagevrio (molnupiravir) for COVID-19 treatment in certain adults patients. Merck and Ridgeback will appeal the decision and request a re-examination of the CHMP’s opinion. Related: Merck’s COVID-19 Treatment Fails To Prevent […]

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Paul Bradbury Executive Summary Concentrix (NASDAQ: CNXC ) is well-positioned to benefit from the growing demand for CX services, as it has a diverse range of clients across industries and geographies. The company has also been successful in expanding its offerings through strategic acquisitions, which has helped to enhance its capabilities and broaden its customer base. While doing so, Concentrix has demonstrated consistent revenue growth, strong profitability, and healthy cash flow generation. The company has also set ambitious growth targets for the coming years, which I believe are achievable given its strong track record and favorable industry tailwinds. At current prices, I believe shares of Concentrix offer an attractive entry point and can generate a 3-year IRR in excess of 20%. Company Overview Concentrix is a global business services company that provides technology-enabled customer engagement and business performance solutions. The company offers a wide range of services, including customer care, technical support, sales, and digital marketing. They help businesses optimize their operations and improve customer experience by leveraging their expertise in data analytics, automation, and digital transformation. Concentrix works with clients across various industries, including technology, telecommunications, healthcare, and finance. With a global workforce of over 225,000 employees, Concentrix […]

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Dorion Renaud Founder and CEO, Buttah Skin More from WWD The Beauty Industry’s Top 20 Most Beloved Moisturizers Miss Universe National Costumes 2023: All the Looks Inside the Beauty Inc Awards Breakfast 2022 “Rich Dad, Poor Dad” by Robert T. Kiyosaki and Sharon Lechter “This is the most impactful business book I’ve read. It’s a great tool to understand how to manage money and your income, and the advice in the book is written specifically for anyone to be able to digest easily.” Anna Teal CEO, Aromatherapy Associates “Future-Engage-Deliver: The Essential Guide to Your Leadership” “I actually find digesting business books quite tricky and have learnt more from podcasts and practical courses. That said, “Future-Engage-Deliver” came at a pivotal point in my career. It carries a very simple but powerful leadership philosophy that has stood me well in the 15 years since I was taught it and holds as true today as it did then. Transforming culture, performance or a business isn’t possible unless you follow the fundamentals of that approach — paint a clear picture of the future, engage stakeholders on why it matters and what it will mean to them, and then outline the plan, timings and […]

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Small errors or inefficiencies can cost your company time . Inefficiency can cost companies anywhere from 20% to 30% of their revenue annually, so it’s worth investigating every way you can streamline and increase productivity. Time lost between converting and re-converting different files may start to add up. PDFs are common, but not every computer has advanced PDF tools to access, edit, and create them. Tax season is here, which is a good time to start looking for time-saving solutions like PDF Expert One. A one-time purchase of this lifetime license gives a user the ability to edit, merge, and sign PDFs — and that’s just the start. PDF Expert is an all-in-one PDF tool . Edit PDF documents without converting between file formats in moments. Users can even add entire paragraphs, insert images , and add links. Taking notes on PDFs may also be easier when you can annotate them directly. PDF Expert lets you highlight text, insert notes, and write in the margins. You can also convert between Word and PDF, among other common file types. PDFs keep their formatting when opened on different devices, so you can make sure your clients, partners, and customers see exactly […]

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