Orchard Therapeutics Provides Business Update and Reports 2022 Financial Results

Orchard Therapeutics Provides Business Update and Reports 2022 Financial Results

Orchard Therapeutics (Europe) Limited OTL-200 pre-BLA meeting granted for second quarter of 2023 following productive clinical Type B meeting with the U.S. Food and Drug Administration (FDA) Strategic financing from leading healthcare investors provides up to $188 million of additional capital upon achievement of key milestones $18.8M of Libmeldy revenue in 2022 with growth expected in 2023 from ongoing commercial expansion activities in Europe Newborn screening studies have confirmed three cases of metachromatic leukodystrophy (MLD) with 96,000 babies screened globally to date Company to webcast conference call today at 8:00 a.m. ET BOSTON and LONDON, March 06, 2023 (GLOBE NEWSWIRE) — Orchard Therapeutics (Nasdaq: ORTX), a global gene therapy leader, today announced business updates along with its financial results for the quarter and year ended December 31, 2022. The company will host a live webcast at 8:00 a.m. ET that will be available under “News & Events” in the Investors & Media section of the company’s website at www.orchard-tx.com . Analysts wishing to participate in the question and answer session should use this link . A replay of the webcast will be archived on the Orchard website following the presentation. “We are already building tremendous momentum in 2023 across […]

LOWE'S 'INTO THE BLUE: PRODUCT PITCH EVENT' RETURNS, INVITING ENTREPRENEURS AND BUSINESS OWNERS TO APPLY FOR OPPORTUNITY TO BECOME LOWE'S SUPPLIERS

LOWE’S ‘INTO THE BLUE: PRODUCT PITCH EVENT’ RETURNS, INVITING ENTREPRENEURS AND BUSINESS OWNERS TO APPLY FOR OPPORTUNITY TO BECOME LOWE’S SUPPLIERS

Innovative suppliers of all sizes can apply for company’s largest and most impactful live sourcing event now through March 20 MOORESVILLE, N.C., March 6, 2023 /PRNewswire/ — For the second time, Lowe’s is calling on entrepreneurs and businesses of all sizes nationwide and internationally to apply for "Into the Blue: Lowe’s Product Pitch Event," the home improvement retailer’s largest and most impactful live product sourcing event. Now through March 20, interested businesses with ready-for-market products can apply at Lowes.com/Suppliers . For the second time, Lowe’s is calling on entrepreneurs and businesses of all sizes nationwide and internationally to apply for “Into the Blue: Lowe’s Product Pitch Event,” the home improvement retailer’s largest and most impactful live product sourcing event. The inaugural Into the Blue event was held in 2022, during which 270 suppliers were selected to pitch their products live to Lowe’s merchandising team. As a result, Lowe’s is now proudly onboarding over 170 new vendors in each of our merchandising business areas, home décor, hardlines and building products. "Last November, Into the Blue left us inspired and motivated by hard-working entrepreneurs looking for an opportunity to reach a larger audience," said Bill Boltz, executive vice president, merchandising. "We […]

ADM homes in on quality of earnings

ADM homes in on quality of earnings

Photo: ©JETCITYIMAGE – STOCK.ADOBE.COM FORT LAUDERDALE, FLA. — With a renewed organizational focus on customers begun several years ago, ADM has been emphasizing the importance of quality of earnings in addition to quantity, seeking a return on invested capital and synergies that can smooth out volatile markets over the long haul and helping farmers embrace regenerative agriculture in a more secure, value-added future. ADM underwent an exercise a few years ago in which the global agribusiness looked at all of its businesses, down to specific assets, identified the strategic fit and looked at the return structure associated with those businesses and assets. As a result, a number of facilities and businesses were adjusted or sold, said Greg Morris, president, Ag Services and Oilseeds at ADM, who was speaking at the Bank of America 2023 Global Agriculture and Materials Conference, held March 1-2 in Fort Lauderdale. “We went through a period of time where we made some significant portfolio adjustments, exiting underperforming businesses, low-returning businesses, volatile-returning businesses and replacing those with businesses that we believe were going to have a much more steady trajectory in terms of the earnings growth,” he said Mr. Morris said assets that are high-volume, high-throughput […]

STAAR Surgical: A Good Business That (Almost) Anyone Can Run

STAAR Surgical: A Good Business That (Almost) Anyone Can Run

Jun/iStock via Getty Images Preamble Since my previous article on STAAR Surgical (NASDAQ: STAA ) published on 28 November 2022, the stock price has risen 34.6% from $58.93 to a high of $79.34 on 2 Feb 2023 but not before it first cratered 20% to $46.82 on 28 December 2022. And from that February high of $79.34 it crashed again, this time by 30% to $55.39 on 28 February 2023. Two reasons led me to invest in STAA in the first place – the quality of the leadership and the fundamentals of the company. In my previous article, I focused on CEO Caren Mason who led the transformational change at STAA that improved the business fundamentals and brought it to new heights. Then, there was a CEO change in December 2022. I know little about the new CEO Mr. Thomas Frinzi, other than he was appointed to STAAR’s Board of Directors in June 2020 and had experience in the ophthalmic and medical device industries at both large, well-established companies and innovative start-ups. Prior to joining STAA, he served as Worldwide President, Surgical for Johnson & Johnson’s ( JNJ ) Vision business, and previously served as Senior Vice President of […]

LastPass aftermath leaves long to-do list for business customers

LastPass aftermath leaves long to-do list for business customers

Hispanolistic via Getty Images Business administrators that entrusted LastPass with their organization’s login credentials have some work to do to regain a defensive posture. A monthslong cyberattack compromised most of the highly sensitive customer account data held by the password manager, with the exception of users’ master passwords, which LastPass said it doesn’t store or maintain. The exposure is broad and potentially ruinous for organizations that don’t take additional steps to protect against unauthorized enterprise account access. Access now➔ Business administrators need to assess their organization’s risk across multiple components and heed the recommendations LastPass said it shared last week in a security bulletin with about 100,000 business customers. Here’s the most high-level actions LastPass shared with its business customers in a top-down order to prioritize response (advice for individual customers can be viewed here ): Master Passwords Usernames and master passwords, which create a unique encryption key, should be at least 12 characters long, according to LastPass. The longer the master password the better, particularly when all available character sets are used. “Remember that length wins over complexity,” LastPass said. Administrators should set policies that require: A minimum character length Minimum character sets A change when reuse is […]

Nokia Oyj : and Indosat support Indonesia's Digital Transformation Agenda with private wireless agreement #MWC23

Nokia Oyj : and Indosat support Indonesia’s Digital Transformation Agenda with private wireless agreement #MWC23

Nokia and Indosat support Indonesia’s Digital Transformation Agenda with private wireless agreement #MWC23 Indosat Ooredoo Hutchison and Nokia extend partnership with Memorandum of Understanding to accelerate Indonesia’s digital transformation. Industrial-grade private wireless maximizes use of Industry 4.0 technologies to boost productivity, increase automation, and enhance safety and security. 02 March 2023 Espoo, Finland – Nokia and Indosat Ooredoo Hutchison (IOH) today announced they have signed a Memorandum of Understanding (MoU) to launch an advanced enterprise campus private wireless network in key regions across the country. As part of the MoU, the Nokia private wireless solution will be deployed in East and Central Java, Sumatera and Kalimantan. The MoU marks a shared vision of IOH and Nokia to accelerate Indonesia’s digital transformation agenda. The collaboration is designed to elevate industrial operations with highly reliable, low-latency connectivity in tandem with a program closely linked to the government’s digital economic development plan. Zones vital to economic growth in Indonesia will be boosted by an advanced industrial network and, in a country comprised of more than 17,000 islands, a planned port solution will improve operational efficiency with a high-grade digitalization platform. Overall, the MoU seeks to build a more agile business environment that […]

Third annual Digital Transformation Jordan conference set to begin in Amman

Third annual Digital Transformation Jordan conference set to begin in Amman

The two-day event, on March 6 and 7, will feature 30-plus speakers from more than 10 countries who will take part in presentations and panel discussions on a range of topics ‘We hope to strengthen the country’s digital transformation by encouraging more local IT talent to be part of the digitalization process,’ Jordan’s digital economy minister said Senior government decision-makers, industry leaders, international technology consultants and other experts will gather in Amman next week for the third annual Digital Transformation Jordan conference. “We are keen to modernize IT (information technology) projects in Jordan and address e-government projects across government agencies to keep pace with the progress of digital transformation innovations that improve the delivery of government services and enhance the efficiency of government performance,” said Ahmad Al-Hanandeh, Jordan’s minister of digital economy and entrepreneurship. “We also hope to strengthen the country’s digital transformation by encouraging more local IT talent to be part of the digitalization process.” The two-day event, which begins on March 6, is organized with the endorsement of Al-Hanandeh’s ministry. More than 30 speakers from more than 10 countries will take part in presentations and panel discussions on topics such as: powering the digital economy with data-first […]

Coffee Talk: Digital Transformation & AIOps: The Future of IT

Coffee Talk: Digital Transformation & AIOps: The Future of IT

Join us live to qualify to receive $5 Starbucks gift card!* “Hmmm, I hadn’t thought of that!” When you implement AIOps, you’ll find yourself saying that often! The rise of automation has helped network operators do a better and better job optimizing their networks and providing reliable service. One of the most inflential driver of those improvements is your learning more and more about your networks as you manage them, and applying that learning where and when you can. Thanks to Machine Learning (ML), Artificial Intelligence (AI) connected to your network learns more about it faster than we humans ever could. When such AI becomes one of your partners in managing the network, its referred to as AIOps. AIOps collects, analyzes, and makes recommendations based on a variety of sources, including the network traffic itself, environmental factors, and data coming from other systems connected to yours. In many cases, AIOps will identify opportunities for network improvement that you hadn’t thought of! In this session, we’ll examine the growth of AIOps, discussing not only how it can be applied to accelerate improvement to networks, but also how cautious humans can assure that it remains under control and positively productive. Register […]

FlashBlade//E to open up new opportunities in Australia

FlashBlade//E to open up new opportunities in Australia

Pure Storage’s all-flash strategy has previously catered for the performance end of the storage market, but its new FlashBlade//E can displace hard disk arrays for workloads involving unstructured data storage, such as data lakes, and data protection and imaging repositories. Amy Rushall, the supplier’s area vice-president for Australia and New Zealand (ANZ), said when she joined the company seven years ago that achieving the US$1 per gigabyte price point for flash storage was exciting, but FlashBlade//E represents “an incredible opportunity” with its acquisition cost of US$0.20 per gigabyte before data reduction, including three years of service. “This gives us a new addressable market, something that we just couldn’t touch before,” said Rushall. “Our dream of getting to the all-flash data centre is coming true.” In Australia, “this is going to open up those workloads where we couldn’t necessarily compete on price…anything in the unstructured data space – data lakes , data protection. Now we have an answer for them,” she added. Rushall noted that some organisations are also repatriating public cloud workloads to on-premise systems for cost reasons, adding that FlashBlade//E “will be the opportunity for us to provide a product where they could potentially bring workloads back from […]

Gold emerges a strong buying opportunity

Gold emerges a strong buying opportunity

Last week, precious metals markets remained in high demand due to market sentiments regarding additional rate hikes by the Federal Reserve in the coming months to combat high inflation. The inflation rate remains elevated, and January PCE data indicates. The PCE increased by 5.38% in January compared to the same month last year, and it continues to advance at a monthly rate of 0.5%. Inflation is a concern of higher gold prices, but central bank buying of the metal is also a source of high gold prices. The high inflation in the economy suggests that any pullback in the gold market must be treated as a strong buying opportunity. Due to geopolitical tensions and fiat currency risk, central banks see the need for hard currency in reserves. According to the World Gold Council, central banks purchased 31 tonnes of gold in January, representing a 16% monthly increase. China is the leading purchaser of gold reserves. In 2022, central banks increased their gold reserves by 150% compared to 2021. According to the World Gold Council, the monetary gold demand will continue in 2023. Gold market analysis The gold market has established a solid bottom near $1600 and continues to rise. […]